Titrate siRNAs. Using the lowest possible concentration of siRNA may help avoid unwanted side effects, says Taylor. "Off-target effects can be dose-dependent." Before you start your study, run ...
New findings point to an opportunity to improve therapies that use small RNAs to silence disease-causing genes, potentially including those involved in cancer. In everyday life, when things turn out ...
Since the discovery of small RNAs, RNA interference (RNAi) has become a popular alternative to technologies such as gene disruption and chemical inhibition. RNAi is an extremely powerful tool for ...
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