Find out more about how more than 40% of adults with chronic headache conditions experience depression or anxiety.

Chronic pain and depression are major health crises in the United States, significantly affecting the quality of life for millions. Traditional treatments often fall short in providing relief, leading ...

Young people with chronic pain are three times more likely than their peers to also have clinical anxiety or depression, a new review has found. Led by researchers at Macquarie University, the study ...

The physical symptoms of depression are often ignored or confused for something else, like a medical problem. Fatigue, ...

Patients with chronic depression can be differentiated from those with episodic depression according to their levels of cognitive–behavioural and emotional avoidance, study findings suggest.

The investigators identified a total of 376 relevant studies from 50 countries, including 347,468 individuals (70% of whom were female) with chronic pain. The pooled prevalence rates for depression ...

Li’s study, “TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain," was recently published in The Journal of Clinical ...

Study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging illuminates the role of the ventral tegmental area in reward processing, motivation, and emotional regulation Depression affects ...

Chronic inflammation may trigger or worsen depression, especially in those with autoimmune or chronic conditions. Depression is a widespread mental health condition with many possible causes.

Millions of people suffering from chronic fatigue find themselves in a frustrating diagnostic limbo. At first glance, their symptoms mirror those of depression, leading to frequent misdiagnosis and ...

—A new literature review examines the impact of depression—and the medications that are commonly prescribed to help treat it—on chronic liver disease outcomes. Candy Gulko, a freelance medical writer, ...